Selected Publications

Sun, AX, Londono, R, Hudnall, ML, Tuan, RS, Lozito, TP. Differences in neural stem cell identity and differentiation capacity drive divergent regenerative outcomes in lizards and salamanders. Proc Natl Acad Sci USA. 2018 Aug 28;115 (35):E8256-E8265. doi: 10.1073/pnas.1803780115. PubMed PMID:30104374 PubMed Central PMC6126763.

Londono, R, Wenzhong, W, Wang, B, Tuan, RS, Lozito, TP. Cartilage and muscle cell fate and origins during lizard tail regeneration. Front Bioeng Biotechnol. 2017 Nov;5 :70. doi: 10.3389/fbioe.2017.00070. PubMed PMID:29164111 PubMed Central PMC5673626.

Lozito, TP, Tuan, RS. Lizard tail regeneration as an instructive model of enhanced healing capabilities in an adult amniote. Connect Tissue Res. 2017 Mar;58 (2):145-154. doi: 10.1080/03008207.2016.1215444. PubMed PMID:27459585 PubMed Central PMC5484412.

Lozito, TP, Tuan, RS. Lizard tail skeletal regeneration combines aspects of fracture healing and blastema-based regeneration. Development. 2016 Aug;143 (16):2946-57. doi: 10.1242/dev.129585. PubMed PMID:27387871 PubMed Central PMC5004880.

Lozito, TP, Tuan, RS. Lizard tail regeneration: Regulation of two distinct cartilage regions by Indian Hedgehog. Dev Biol. 2015 Mar;399 (2):249-62. doi: 10.1016/j.ydbio.2014.12.036. PubMed PMID:25596336.

Lozito, TP, Tuan, RS. Endothelial and cancer cells interact with mesenchymal stem cells via both microparticles and secreted factors. J Cell Mol Med. 2014 Dec;18 (12):2372-84. doi: 10.1111/jcmm.12391. PubMed PMID:25250510 PubMed Central PMC4302643.

Lozito TP*, Lin H*, Alexander PG, Gottardi R, Tuan RS (*Equal Author Contribution). Stem cell-based microphysiological osteochondral system to model tissue response to interleukin-1β. Mol Pharm. 2014 Jul;11(7):2203-12. doi: 10.1021/mp500136b. PubMed PMID:24830762 PubMed Central PMC4086740.

Alexander PG, Gottardi R, Lin H, Lozito TP, Tuan RS. Three-dimensional osteogenic and chondrogenic systems to model osteochondral physiology and degenerative joint diseases. Exp Biol Med. 2014 Sep;239(9):1085-95. doi: 10.1177/1535370214539232. PubMed PMID:24994814 PubMed Central PMC5413932.

Lozito TP, Jackson WM, Nesti LJ, Tuan RS. Human mesenchymal stem cells generate a distinct pericellular zone of MMP activities via binding of MMPs and secretion of high levels of TIMPs. Matrix Biol. 2014 Feb;34:132-43. doi: 10.1016/j.matbio.2013.10.003. PubMed PMID:24140982.

Cui, C, Chatterjee, B, Lozito, TP, Zhang, Z, Francis, RJ, Yagi, H et al.. Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013 Nov;11 (11):e1001720. doi: 10.1371/journal.pbio.1001720. PubMed PMID:24302887 PubMed Central PMC3841097.

Lozito TP, Tuan RS. Endothelial cell microparticles act as centers of MMP-2 activation and for vascular matrix remodeling. J Cell Physiol. 2012 Feb;227(2):534-49. doi: 10.1002/jcp.22744. PubMed PMID:21437907 PubMed Central PMC3205212.

Jackson WM, Lozito TP, Djouad F, Kuhn NZ, Nesti LJ, Tuan RS. 2011. Differentiation and regeneration potential of mesenchymal progenitor cells derived from traumatized muscle tissue. J Cell Mol Med. 2011 Nov;15(11):2377-88. doi: 10.1111/j.1582-4934.2010.01225.x. PubMed PMID:21129154 PubMed Central PMC3131486.

Lozito TP, Tuan RS. Mesenchymal stem cells inhibit both endogenous and exogenous MMPs via secreted TIMPs. J Cell Physiol. 2011 Feb;226(2):385-96. doi: 10.1002/jcp.22344. PubMed PMID:20665704.

Lozito TP, Kuo CK, Taboas JM, Tuan RS. Human mesenchymal stem cells express vascular cell phenotypes upon interactions with endothelial cell matrix. J Cell Biochem. 2009 Jul;107(4):714-22. doi: 10.1002/jcb.22167. PubMed PMID:19415687 PubMed Central PMC5543930.

Lozito TP, Taboas JM, Kuo CK, Tuan RS. Mesenchymal stem cell modification of endothelial cell matrix regulates their vascular differentiation. J Cell Biochem. 2009 Jul;107(4):706-13. doi: 10.1002/jcb.22166. PubMed PMID:19415686.