USC Stem Cell study breaks the silence on how fish and lizards regenerate hearing

A new USC Stem Cell study published in the Proceedings of the National Academy of Sciences (PNAS) has identified key gene regulators that enable some deafened animals—including fish and lizards—to naturally regenerate their hearing. The findings could guide future efforts to stimulate the regeneration of sensory hearing cells in patients with hearing loss and balance Read More…

Aided by stem cells, a lizard regenerates a perfect tail for the first time in 250 million years

Lizards can regrow severed tails, making them the closest relative to humans that can regenerate a lost appendage. But in lieu of the original tail that includes a spinal column and nerves, the replacement structure is an imperfect cartilage tube. Now, for the first time, a USC-led study in Nature Communications describes how stem cells Read More…

Lizards’ immune systems are not only for fighting germs, but also for regrowing severed tails

The human immune system has been getting a bad rap lately. However, the lizard immune system is finally receiving its due credit for enabling lizards to regrow severed tails. In a recent study in the Journal of Immunology and Regenerative Medicine, researchers from USC and the University of Pittsburgh describe how immune cells, called phagocytes, Read More…